A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia
Author:
Publisher
Springer Science and Business Media LLC
Subject
Computer Science Applications,History,Education
Link
http://www.nature.com/articles/s41698-018-0061-2.pdf
Reference11 articles.
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3. Minter, R. R., Sandercock, A. M. & Rust, S. J. Phenotypic screening-the fast track to novel antibody discovery. Drug Discov. Today Technol. 23, 83–90 (2017).
4. Frendeus, B. Function-first antibody discovery: embracing the unpredictable biology of antibodies. Oncoimmunology 2, 20 (2013).
5. Söderlind, E. et al. Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries. Nat. Biotechnol. 18, 852–856 (2000).
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