Case study: patient-derived clear cell adenocarcinoma xenograft model longitudinally predicts treatment response
Author:
Publisher
Springer Science and Business Media LLC
Subject
Computer Science Applications,History,Education
Link
http://www.nature.com/articles/s41698-018-0060-3.pdf
Reference34 articles.
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3. Gao, H. et al. High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response. Nat. Med. 21, 1318–1325 (2015).
4. Hidalgo, M. et al. A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer. Mol. Cancer Ther. 10, 1311–1316 (2011).
5. Garrido-Laguna, I. et al. Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer. Clin. Cancer Res. 17, 5793–5800 (2011).
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