Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/35002615.pdf
Reference27 articles.
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3. Peel, S. A., Merritt, S. C., Handy, J. & Baric, R. S. Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 48, 385–397.
4. Cowman, A. F., Galatis, D. & Thompson, K. J. Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proc. Natl Acad. Sci. USA 91, 1143–1147 (1994).
5. Peel, S. A., Bright, P., Yount, B., Handy, J. & Baric, R. S. A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 51, 648– 658 (1994).
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