Bridging Clinical Outcomes of Canakinumab Treatment in Patients With Rheumatoid Arthritis With a Population Model of IL-1β Kinetics
Author:
Affiliation:
1. Department of Pharmaceutical Sciences; University at Buffalo, The State University of New York; Buffalo New York USA
2. Department of Modelling & Simulation; Novartis Pharma AG; Basel Switzerland
Publisher
Wiley
Subject
Pharmacology (medical),Modelling and Simulation
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2012.6/fullpdf
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4. Cytokine pathways and joint inflammation in rheumatoid arthritis;Choy;N. Engl. J. Med,2001
5. Modeling and simulation of abatacept exposure and interleukin-6 response in support of recommended doses for rheumatoid arthritis;Roy;J. Clin. Pharmacol,2007
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