A PBPK Model to Predict Disposition of CYP3A-Metabolized Drugs in Pregnant Women: Verification and Discerning the Site of CYP3A Induction-Reference-Cited by-同舟云学术

A PBPK Model to Predict Disposition of CYP3A-Metabolized Drugs in Pregnant Women: Verification and Discerning the Site of CYP3A Induction

Published:2012-09 Issue:9 Volume:1 Page:3
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT: Pharmacometrics & Systems Pharmacology

Author:

Ke AB¹²,Nallani SC²,Zhao P²,Rostami-Hodjegan A³⁴,Unadkat JD¹

Affiliation:

1. Department of Pharmaceutics; University of Washington; Seattle Washington USA

2. Department of Clinical Pharmacology; Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration; Silver Spring Maryland USA

3. School of Pharmacy and Pharmaceutical Sciences, University of Manchester; Manchester UK

4. Simcyp Limited; Sheffield UK

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2012.2/fullpdf

Reference43 articles.

1. Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population;Glover;Am. J. Obstet. Gynecol.,2003

2. Prescription drug use in pregnancy;Andrade;Am. J. Obstet. Gynecol.,2004

3. Effect of pregnancy on the pharmacokinetics of antihypertensive drugs;Anderson;Clin. Pharmacokinet.,2009

4. Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study;Hebert;Clin. Pharmacol. Ther.,2008

5. Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women;Unadkat;Antimicrob. Agents Chemother.,2007

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