Genetic deletion of PKR abrogates TNF-induced activation of IκBα kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation-Reference-Cited by-同舟云学术

Genetic deletion of PKR abrogates TNF-induced activation of IκBα kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation

Published:2006-08-21 Issue:8 Volume:26 Page:1201-1212
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Takada Y,Ichikawa H,Pataer A,Swisher S,Aggarwal B B

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/1209906.pdf

Reference65 articles.

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2. Aggarwal BB . (2004). Nuclear factor-kappaB: the enemy within. Cancer Cell 6: 203–208.

3. Balachandran S, Kim CN, Yeh WC, Mak TW, Bhalla K, Barber GN . (1998). Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling. EMBO J 17: 6888–6902.

4. Bandyopadhyay SK, de La Motte CA, Williams BR . (2000). Induction of E-selectin expression by double-stranded RNA and TNF-alpha is attenuated in murine aortic endothelial cells derived from double-stranded RNA-activated kinase (PKR)-null mice. J Immunol 164: 2077–2083.

5. Bonnet MC, Weil R, Dam E, Hovanessian AG, Meurs EF . (2000). PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex. Mol Cell Biol 20: 4532–4542.

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