Reactivation of mutant p53: molecular mechanisms and therapeutic potential
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/1210295.pdf
Reference101 articles.
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3. Bargonetti J, Manfredi JJ, Chen X, Marshak DR, Prives C . (1993). A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev 7: 2565–2574.
4. Bell S, Klein C, Muller L, Hansen S, Buchner J . (2002). p53 contains large unstructured regions in its native state. J Mol Biol 322: 917–927.
5. Bensaad K, Le Braas M, Unsal K, Strano S, Blandino G, Tominaga O et al. (2003). Change of conformation of the DNA-binding domain of p53 is the only key element for binding of and interference with p73. J Biol Chem 278: 10546–10555.
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