Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/1210687.pdf
Reference37 articles.
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2. Chang PC, Chi CW, Chau GY, Li FY, Tsai YH, Wu JC et al. (2006). DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control. Oncogene 25: 1991–2003.
3. Chao CH, Chen CM, Cheng PL, Shih JW, Tsou AP, Wu Lee YH . (2006). DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor. Cancer Res 66: 6579–6588.
4. Chuang RY, Weaver PL, Liu Z, Chang TH . (1997). Requirement of the DEAD-Box protein ded1p for messenger RNA translation. Science 275: 1468–1471.
5. De Benedetti A, Graff JR . (2004). eIF-4E expression and its role in malignancies and metastases. Oncogene 23: 3189–3199.
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