Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL

Author:

Bae S I,Cheriyath V,Jacobs B S,Reu F J,Borden E C

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference23 articles.

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3. Byun D, Cho K, Ryu B, Lee M, Kang M, Kim H et al. (2003). Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas. Cancer Res 63: 7068.

4. Chawla-Sarkar M, Bae S, Reu F, Jacobs B, Lindner D, Borden E . (2004). Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ 11: 915.

5. Chawla-Sarkar M, Lindner D, Liu Y, Williams B, Sen G, Silverman R et al. (2003). Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis 8: 237.

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