Reciprocal DNA topoisomerase II cleavage events at 5′-TATTA-3′ sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing

Author:

Whitmarsh Ryan J,Saginario Charles,Zhuo Ya,Hilgenfeld Eva,Rappaport Eric F,Megonigal Maureen D,Carroll Martin,Liu Mingli,Osheroff Neil,Cheung Nai-Kong V,Slater Diana J,Ried Thomas,Knutsen Turid,Blair Ian A,Felix Carolyn A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference69 articles.

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