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Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins

Published:2007-03-12 Issue:38 Volume:26 Page:5553-5563
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Ostler K R,Davis E M,Payne S L,Gosalia B B,Expósito-Céspedes J,Beau M M Le,Godley L A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/1210351.pdf

Reference52 articles.

1. Aggerholm A, Holm MS, Guldberg P, Olesen LH, Hokland P . (2006). Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients. Eur J Haematol 76: 23–32.

2. Bachman KE, Park BH, Rhee I, Rajagopalan H, Herman JG, Baylin SB et al. (2003). Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell 3: 89–95.

3. Bartel F, Taubert H, Harris LC . (2002). Alternative and aberrant splicing of MDM2 mRNA in human cancer. Cancer Cell 2: 9–15.

4. Beaulieu N, Morin S, Chute IC, Robert M-F, Nguyen H, MacLeod AR . (2002). An essential role for DNA methyltransferase DNMT3B in cancer cell survival. J Biol Chem 277: 28176–28181.

5. Bestor TH . (2000). The DNA methyltransferases of mammals. Hum Molec Genet 9: 2395–2402.

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