The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/1210248.pdf
Reference18 articles.
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2. Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K . (2006). Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes and Dev 20: 1123–1136.
3. Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K . (2003). EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J 20: 5323–5335.
4. Cao R, Zhang Y . (2004). SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell 15: 57–67.
5. Garde SV, Basrur VS, Li L, Finkelman MA, Krishnan A, Wellham L et al. (1999). Prostate secretory protein (PSP94) suppresses the growth of androgen-independent prostate cancer cell line (PC-3) and xenografts by inducing apoptosis. Prostate 38: 118–125.
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