Can one overcome “unhealthy genes”?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/s41525-019-0099-2.pdf
Reference24 articles.
1. Khera, A. V. & Kathiresan, S. Genetics of coronary artery disease: discovery, biology and clinical translation. Nat. Rev. Genet. 18, 331–344 (2017).
2. Berberich, A. J. & Hegele, R. A. The complex molecular genetics of familial hypercholesterolaemia. Nat. Rev. Cardiol. 16, 9–20 (2019).
3. Besseling, J., Hovingh, G. K., Huijgen, R., Kastelein, J. J. P. & Hutten, B. A. Statins in familial hypercholesterolemia: consequences for coronary artery disease and all-cause mortality. J. Am. Coll. Cardiol. 68, 252–260 (2016).
4. Hegele, R. A. et al. Clinical application of deoxyribonucleic-acid markers in a Utah family with hypercholesterolemia. Am. J. Cardiol. 63, 109–112 (1989).
5. Hartz, J., Hegele, R. A. & Wilson, D. P. Low LDL cholesterol-friend or foe? J. Clin. Lipidol. 13, 367–373 (2019).
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