KSHV-encoded ORF45 activates human NLRP1 inflammasome
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
https://www.nature.com/articles/s41590-022-01199-x.pdf
Reference38 articles.
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2. Mitchell, P. S., Sandstrom, A. & Vance, R. E. The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries. Curr. Opin. Immunol. 60, 37–45 (2019).
3. Taabazuing, C. Y., Griswold, A. R. & Bachovchin, D. A. The NLRP1 and CARD8 inflammasomes. Immunol. Rev. 297, 13–25 (2020).
4. Chavarría-Smith, J., Mitchell, P. S., Ho, A. M., Daugherty, M. D. & Vance, R. E. Functional and evolutionary analyses identify proteolysis as a general mechanism for NLRP1 inflammasome activation. PLoS Pathog. 12, e1006052 (2016).
5. Finger, J. N. et al. Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity. J. Biol. Chem. 287, 25030–25037 (2012).
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