Distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia
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Published:2024-08-13
Issue:9
Volume:25
Page:1607-1622
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ISSN:1529-2908
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Container-title:Nature Immunology
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language:en
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Short-container-title:Nat Immunol
Author:
Markov Nikolay S.ORCID, Ren ZiyouORCID, Senkow Karolina J.ORCID, Grant Rogan A.ORCID, Gao Catherine A.ORCID, Malsin Elizabeth S.ORCID, Sichizya LangoORCID, Kihshen HermonORCID, Helmin Kathryn A.ORCID, Jovisic MilicaORCID, Arnold Jason M.ORCID, Pérez-Leonor Xóchitl G.ORCID, Abdala-Valencia HiamORCID, Swaminathan SuchitraORCID, Nwaezeapu JuluORCID, Kang MengjiaORCID, Rasmussen LukeORCID, Ozer Egon A.ORCID, Lorenzo-Redondo RamonORCID, Hultquist Judd F.ORCID, Simons Lacy M.ORCID, Rios-Guzman EstefanyORCID, Misharin Alexander V.ORCID, Wunderink Richard G.ORCID, Budinger G. R. ScottORCID, Singer Benjamin D.ORCID, Morales-Nebreda LuisaORCID, , Abdala-Valencia Hiam, Rasmussen Luke V., Hultquist Judd, Simmons Lacy, Guzman Estefany R., Alexander Michael J., Alisoltanidehkordi Arghavan, Bailey Joseph I., Bartom Elizabeth T., Bharat Ankit, Bolig Thomas, Borkowski Nicole, Chandel Navdeep S., Clepp Rebecca K., Coleman John, Cuttica Michael J., Cybulski Thaddeus R., Dematte Jane E., Deters Joseph S., Diaz Estefani, Donayre Alvaro, Donnelly Helen K., Fiala Justin A., Gadhvi Gaurav T., Gates Khalilah L., Gatesy Samuel W. M., Go Pearl D., Gottardi Cara J., Green Stefan J., Gusman Elen, Han SeungHye, Hartmann Erica Marie, Hauser Alan R., Horvath Curt M., Hukamdad Mishaal, Hyder Sydney M., Jain Manu, Jonasson Emmy, Joudi Anthony M., Kadar Rachel B., Kalhan Ravi, Kamp David W., Kandpal Manoj, Kidd David A., Klug Zasu M., Korth Erin A., Kruser Jacqueline M., Lawrence Romy, Leibenguth Emily M., Levenson Anne R., Gradone Lindsey D., Liu Gabrielle Y., Lomasney Jon W., Lombardo Theresa A., Lu Ziyan, Ludwig Amy, Mahmoud Ali, McQuattie-Pimentel Alexandra C., Meza Daniel, Mylvaganam Ruben J., Nannapaneni Prasanth, Nozick Sophia, Nunes Amaral Luís A., Patel Radhika, Pawlowski Anna E., Pickens Chiagozie O., Politanska Yuliya, Poor Taylor A., Prickett Michelle H., Qi Chao, Querrey Melissa, Ridge Karen M., Rosenbaum Madeline L., Rosenberg Sharon R., Rowe Timothy, Russell Susan R., Sala Marc A., Schneider Daniel, Schroedl Clara J., Secunda Katharine, Seed Patrick C., Shanes Elisheva D., Shen Jiaxian, Shilatifard Ali, Smith Sean, Sporn Peter H. S., Starren Justin, Stoeger Thomas, Sumner Jack, Sznajder Jacob I., Textor Lindsey N., Thakkar Sanket, Tomic Rade, Tran Betty, Vitale Kaitlyn, Wagh Ajay A., Walter James M., Wehbe Firas, Winter Deborah R., Wolfe Alexis R., Wolfe Lisa F., Yeldandi Anjana V., Yu Zhan, Castellanos Jose, Johnson Lars, Laurenzo Scott, Matias Gabrielle, Olson Emily M., Rowell Jamie, Smith-Nunez Ashley, Szabo Alison, White Brian
Funder
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
Publisher
Springer Science and Business Media LLC
Reference68 articles.
1. Budinger, G. R. S., Misharin, A. V., Ridge, K. M., Singer, B. D. & Wunderink, R. G. Distinctive features of severe SARS-CoV-2 pneumonia. J. Clin. Invest. 131, e149412 (2021). 2. Gao, C. A. et al. Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19. J. Clin. Invest. 133, e170682 (2023). 3. Grant, R. A. et al. Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia. Nature 590, 635–641 (2021). 4. Rydyznski Moderbacher, C. et al. Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity. Cell 183, 996–1012 (2020). 5. Markov, N. S. et al. SCRIPT CarpeDiem dataset: demographics, outcomes, and per-day clinical parameters for critically ill patients with suspected pneumonia (version 1.1.0). PhysioNet https://doi.org/10.13026/5phr-4r89 (2023).
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