Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication-Reference-Cited by-全球学者库

Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication

Published:2021-03-25 Issue:4 Volume:22 Page:423-433
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Guo Haitao,Wang Qi,Ghneim Khader,Wang Li,Rampanelli Elena^ORCID,Holley-Guthrie Elizabeth,Cheng Liang,Garrido Carolina,Margolis David M.^ORCID,Eller Leigh A.,Robb Merlin L.,Sekaly Rafick-Pierre,Chen Xian,Su Lishan,Ting Jenny P.-Y.

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/s41590-021-00898-1.pdf

Reference51 articles.

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2. Palmer, C. S. et al. Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection. AIDS 28, 297–309 (2014).

3. Palmer, C. S., Palchaudhuri, R., Albargy, H., Abdel-Mohsen, M. & Crowe, S. M. Exploiting immune cell metabolic machinery for functional HIV cure and the prevention of inflammaging. F1000Res 7, 125 (2018).

4. Dagenais-Lussier, X. et al. Current topics in HIV-1 pathogenesis: the emergence of deregulated immuno-metabolism in HIV-infected subjects. Cytokine Growth Factor Rev. 26, 603–613 (2015).

5. Gerriets, V. A. & Rathmell, J. C. Metabolic pathways in T cell fate and function. Trends Immunol. 33, 168–173 (2012).

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