SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells
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Published:2022-04-05
Issue:5
Volume:23
Page:781-790
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ISSN:1529-2908
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Container-title:Nature Immunology
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language:en
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Short-container-title:Nat Immunol
Author:
Minervina Anastasia A., Pogorelyy Mikhail V., Kirk Allison M.ORCID, Crawford Jeremy ChaseORCID, Allen E. KaitlynnORCID, Chou Ching-Heng, Mettelman Robert C.ORCID, Allison Kim J., Lin Chun-YangORCID, Brice David C., Zhu Xun, Vegesana Kasi, Wu GangORCID, Trivedi SanchitORCID, Kottapalli Pratibha, Darnell DanielORCID, McNeely Suzanne, Olsen Scott R., Schultz-Cherry StaceyORCID, Estepp Jeremie H., Gaur Aditya, Hoffman James, Mori Motomi, Tang Li, Tuomanen Elaine, Webby Richard, Hakim Hana, Hayden Randall T., Hijano Diego R., Bajracharya Resha, Awad Walid, Van de Velde Lee-Ann, Clark Brandi L., Wilson Taylor L., Souquette Aisha, Castellaw Ashley, Dallas Ronald H., Hodges Jason, Gowen Ashleigh, Russell-Bell Jamie, Sparks James, Wittman David E., Fabrizio Thomas P., Cherry Sean, Roubidoux Ericka Kirkpatrick, Cortez Valerie, Freiden Pamela, Wohlgemuth Nicholas, Whitt Kendall, McGargill Maureen A.ORCID, Wolf JoshuaORCID, Thomas Paul G.ORCID,
Funder
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Reference59 articles.
1. Flemming, A. Omicron, the great escape artist. Nat. Rev. Immunol. https://doi.org/10.1038/s41577-022-00676-6 (2022). 2. Mallajosyula, V. et al. CD8+ T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19. Sci. Immunol. 6, eabg5669 (2021). 3. Rydyznski Moderbacher, C. et al. Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity. Cell 183, 996–1012 (2020). 4. Kundu, R. et al. Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts. Nat. Commun. 13, 80 (2022). 5. Peng, Y. et al. An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease. Nat. Immunol. 23, 50–61 (2022).
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