Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion-Reference-Cited by-同舟云学术

Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion

Published:2023-09-14 Issue:10 Volume:24 Page:1645-1653
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Tillé Laure^ORCID,Cropp Daniela^ORCID,Charmoy Mélanie,Reichenbach Patrick,Andreatta Massimo^ORCID,Wyss Tania^ORCID,Bodley Gabrielle,Crespo Isaac,Nassiri Sina,Lourenco Joao,Leblond Marine M.,Lopez-Rodriguez Cristina^ORCID,Speiser Daniel E.,Coukos George^ORCID,Irving Melita^ORCID,Carmona Santiago J.^ORCID,Held Werner^ORCID,Verdeil Grégory^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

https://www.nature.com/articles/s41590-023-01614-x.pdf

Reference48 articles.

1. Blank, C. U. et al. Defining ‘T cell exhaustion’. Nat. Rev. Immunol. 19, 665–674 (2019).

2. Utzschneider, D. T. et al. T cell factor 1-expressing memory-like CD8+ T cells sustain the immune response to chronic viral infections. Immunity 45, 415–427 (2016).

3. Speiser, D. E., Ho, P. C. & Verdeil, G. Regulatory circuits of T cell function in cancer. Nat. Rev. Immunol. 16, 599–611 (2016).

4. Thommen, D. S. & Schumacher, T. N. T cell dysfunction in cancer. Cancer Cell 33, 547–562 (2018).

5. Cheng, H., Ma, K., Zhang, L. & Li, G. The tumor microenvironment shapes the molecular characteristics of exhausted CD8+ T cells. Cancer Lett. 506, 55–66 (2021).

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