Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/s41590-019-0312-6.pdf
Reference50 articles.
1. Thommen, D. S. & Schumacher, T. N. T cell dysfunction in cancer. Cancer Cell. 33, 547–562 (2018).
2. Ahmadzadeh, M. et al. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 114, 1537–1544 (2009).
3. Zajac, A. J. et al. Viral immune evasion due to persistence of activated T cells without effector function. J. Exp. Med. 188, 2205–2213 (1998).
4. Moskophidis, D., Lechner, F., Pircher, H. & Zinkernagel, R. M. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 362, 758–761 (1993).
5. Wherry, E. J. T cell exhaustion. Nat. Immunol. 12, 492–499 (2011).
Cited by 1100 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Neoadjuvant chemotherapy-induced remodeling of human hormonal receptor-positive breast cancer revealed by single-cell RNA sequencing;Cancer Letters;2024-03
2. Antigen cross-presentation by dendritic cells: A critical axis in cancer immunotherapy;Seminars in Immunology;2024-02
3. Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages;Nature Communications;2024-02-01
4. A novel polysaccharide isolated from Coriolus versicolor polarizes M2 macrophages into an M1 phenotype and reversesits immunosuppressive effect on tumor microenvironment;International Journal of Biological Macromolecules;2024-02
5. Applications of CRISPR Epigenome Editors in Tumor Immunology and Autoimmunity;ACS Synthetic Biology;2024-01-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3