STEEP mediates STING ER exit and activation of signaling-Reference-Cited by-同舟云学术

STEEP mediates STING ER exit and activation of signaling

Published:2020-07-20 Issue:8 Volume:21 Page:868-879
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Zhang Bao-cun,Nandakumar Ramya,Reinert Line S.^ORCID,Huang Jinrong,Laustsen Anders,Gao Zong-liang^ORCID,Sun Cheng-long,Jensen Søren Beck,Troldborg Anne^ORCID,Assil Sonia,Berthelsen Martin F.,Scavenius Carsten^ORCID,Zhang Yan^ORCID,Windross Samuel J.,Olagnier David,Prabakaran Thaneas,Bodda Chiranjeevi^ORCID,Narita Ryo,Cai Yujia^ORCID,Zhang Cong-gang,Stenmark Harald^ORCID,Doucet Christine M.,Noda Takeshi^ORCID,Guo Zheng,Goldbach-Mansky Raphaela,Hartmann Rune^ORCID,Chen Zhijian J.^ORCID,Enghild Jan J.^ORCID,Bak Rasmus O.^ORCID,Thomsen Martin K.,Paludan Søren R.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

https://www.nature.com/articles/s41590-020-0730-5.pdf

Reference54 articles.

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2. Sun, L., Wu, J., Du, F., Chen, X. & Chen, Z. J. Cyclic GMP–AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science339, 786–791 (2013).

3. Wu, J. et al. Cyclic GMP–AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science339, 826–830 (2013).

4. Ishikawa, H. & Barber, G. N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature455, 674–678 (2008).

5. Shang, G., Zhang, C., Chen, Z. J., Bai, X. C. & Zhang, X. Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP. Nature567, 389–393 (2019).

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