Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease
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Published:2021-01-04
Issue:2
Volume:22
Page:128-139
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ISSN:1529-2908
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Container-title:Nature Immunology
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language:en
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Short-container-title:Nat Immunol
Author:
Ozen AhmetORCID, Kasap Nurhan, Vujkovic-Cvijin IvanORCID, Apps Richard, Cheung Foo, Karakoc-Aydiner Elif, Akkelle Bilge, Sari Sinan, Tutar Engin, Ozcay Figen, Uygun Dilara Kocacik, Islek Ali, Akgun Gamze, Selcuk Merve, Sezer Oya Balci, Zhang Yu, Kutluk Gunsel, Topal Erdem, Sayar Ersin, Celikel Cigdem, Houwen Roderick H. J., Bingol Aysen, Ogulur Ismail, Eltan Sevgi Bilgic, Snow Andrew L., Lake Camille, Fantoni Giovanna, Alba Camille, Sellers Brian, Chauvin Samuel D.ORCID, Dalgard Clifton L., Harari Olivier, Ni Yan G., Wang Ming-Dauh, Devalaraja-Narashimha Kishor, Subramanian PooraniORCID, Ergelen Rabia, Artan Reha, Guner Sukru Nail, Dalgic Buket, Tsang John, Belkaid YasmineORCID, Ertem Deniz, Baris Safa, Lenardo Michael J.ORCID
Funder
Division of Intramural Research, National Institute of Allergy and Infectious Diseases Marmara Üniversitesi Turkish National Society of Allergy and Clinical Immunology
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Reference70 articles.
1. Waldmann, T. A., Steinfeld, J. L., Dutcher, T. F., Davidson, J. D. & Gordon, R. S. Jr. The role of the gastrointestinal system in ‘idiopathic hypoproteinemia’. Gastroenterology 41, 197–207 (1961). 2. Ozen, A. et al. CD55 deficiency, early-onset protein-losing enteropathy, and thrombosis. N. Engl. J. Med. 377, 52–61 (2017). 3. Kurolap, A. et al. Loss of CD55 in eculizumab-responsive protein-losing enteropathy. N. Engl. J. Med. 377, 87–89 (2017). 4. Ozen, A. CHAPLE syndrome uncovers the primary role of complement in a familial form of Waldmann’s disease. Immunol. Rev. 287, 20–32 (2019). 5. Mevorach, D. Clearance of dying cells and systemic lupus erythematosus: the role of C1q and the complement system. Apoptosis 15, 1114–1123 (2010).
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