Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis-Reference-Cited by-同舟云学术

Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis

Published:2018-12-10 Issue:1 Volume:20 Page:86-96
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Hatzi Katerina,Geng Huimin,Doane Ashley S.,Meydan Cem,LaRiviere Reed,Cardenas Mariano,Duy Cihangir,Shen Hao,Vidal Maria Nieves Calvo,Baslan Timour,Mohammad Helai P.,Kruger Ryan G.,Shaknovich Rita,Haberman Ann M.,Inghirami Giorgio,Lowe Scott W.,Melnick Ari M.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/s41590-018-0273-1.pdf

Reference54 articles.

1. Mesin, L., Ersching, J. & Victora, G. D. Germinal center B cell dynamics. Immunity 45, 471–482 (2016).

2. Hatzi, K. & Melnick, A. Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis. Trends Mol. Med. 20, 343–352 (2014).

3. Beguelin, W. et al. EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell 23, 677–692 (2013).

4. Beguelin, W. et al. EZH2 and BCL6 cooperate to assemble CBX8-BCOR complex to repress bivalent promoters, mediate germinal center formation and lymphomagenesis. Cancer Cell 30, 197–213 (2016).

5. Bunting, K. L. et al. Multi-tiered reorganization of the genome during B cell affinity maturation anchored by a germinal center-specific locus control region. Immunity 45, 497–512 (2016).

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