The hidden functional diversity of macrophages
Author:
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41590-024-01832-x.pdf
Reference5 articles.
1. Gibbings, S. L. et al. Three unique interstitial macrophages in the murine lung at steady state. Am. J. Respir. Cell Mol. Biol. 57, 66–76 (2017). This study performed deep sequencing on three distinct IMs based on cell-surface markers, aligned IM genes across tissues, and demonstrated classical macrophage functions.
2. Aegerter, H., Lambrecht, B. N. & Jakubzick, C. V. Biology of lung macrophages in health and disease. Immunity 55, 1564–1580 (2022). This review highlights the heterogeneity and functionality of pulmonary macrophages and provides scRNA-seq and protein expression data that define lung mononuclear phagocytes.
3. Lee, S. H. et al. Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis. Nat. Commun. 14, 7852 (2023). This study targets specific chemokine-expressing skin IMs and demonstrates their functional role in skin disease.
4. Mould, K. J. et al. Airspace macrophages and monocytes exist in transcriptionally distinct subsets in healthy adults. Am. J. Respir. Crit. Care Med. 203, 946–956 (2021). This study showed the extent of airspace macrophage subset heterogeneity in healthy human lungs via scRNA-seq.
5. Li, X. et al. ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF. Life Sci, Alliance 5, e202201458 (2022). This study supports the findings in ref. 4 and identified 12 functionally distinct alveolar macrophage subsets such as various chemokine-expressing AM subsets.
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3