BCG immunization induces CX3CR1hi effector memory T cells to provide cross-protection via IFN-γ-mediated trained immunity
Author:
Funder
Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41590-023-01739-z.pdf
Reference77 articles.
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3. Benn, C. S., Netea, M. G., Selin, L. K. & Aaby, P. A small jab - a big effect: nonspecific immunomodulation by vaccines. Trends Immunol. 34, 431–439 (2013).
4. Garly, M. L. et al. BCG scar and positive tuberculin reaction associated with reduced child mortality in West Africa. A non-specific beneficial effect of BCG? Vaccine 21, 2782–2790 (2003).
5. Prentice, S. et al. BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial. Lancet Infect. Dis. 21, 993–1003 (2021).
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