Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/mi201282.pdf
Reference67 articles.
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2. Yukl, S. et al. Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J. Infect. Dis. 202, 1553–1561 (2010).
3. Hofer, U. & Speck, R.F. Disturbance of gut-associated lymphoid tissue is associated with disease progression in chronic HIV infection. Semin. Immunopathol. 31, 257–266 (2009).
4. Brenchley, J.M. et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 2004, 749–759 (2004).
5. Mehandru, S. et al. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites. J. Exp. Med. 200, 761–770 (2004).
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