High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation

Author:

Long-Boyle J R,Green K G,Brunstein C G,Cao Q,Rogosheske J,Weisdorf D J,Miller J S,Wagner J E,McGlave P B,Jacobson P A

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference43 articles.

1. Baron F, Storb R . Allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning as treatment for hematologic malignancies and inherited blood disorders. Mol Ther 2006; 13: 26–41.

2. Brockman RW, Cheng YC, Schabel Jr FM, Montgomery JA . Metabolism and chemotherapeutic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase. Cancer Res 1980; 40: 3610–3615.

3. Dow LW, Bell DE, Poulakos L, Fridland A . Differences in metabolism and cytotoxicity between 9-beta-D arabinofuranosyladenine and 9-beta-D-arabinofuranosyl-2-fluoroadenine in human leukemic lymphoblasts. Cancer Res 1980; 40: 1405–1410.

4. Maris MB, Niederwieser D, Sandmaier BM, Storer B, Stuart M, Maloney D et al. HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignancies. Blood 2003; 102: 2021–2030.

5. Brunstein CG, Barker JN, Weisdorf DJ, DeFor TE, Miller JS, Blazar BR et al. Umbilical cord blood transplantation after non-myeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease. Blood 2007; 110: 3064–3070.

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