Pharmacological LRRK2 kinase inhibition induces LRRK2 protein destabilization and proteasomal degradation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep33897.pdf
Reference60 articles.
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3. Paisan-Ruiz, C. LRRK2 gene variation and its contribution to Parkinson disease. Hum Mutat . 30, 1153–1160 (2009).
4. Lill, C. M. et al. Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson’s Disease Genetics: The PDGene Database. PLoS Genet . 8, e1002548 (2012).
5. Ross, O. A. et al. Association of LRRK2 exonic variants with susceptibility to Parkinson’s disease: a case-control study. Lancet Neurol . 10, 898–908 (2011).
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