Hope for resistant hypertension through BrigHTN and PRECISION
Author:
Publisher
Springer Science and Business Media LLC
Subject
Nephrology
Link
https://www.nature.com/articles/s41581-023-00676-2.pdf
Reference10 articles.
1. Chobanian, A. V. Shattuck Lecture. The hypertension paradox — more uncontrolled disease despite improved therapy. N. Engl. J. Med. 361, 878–887 (2009).
2. Carey, R. M. et al. Resistant hypertension: detection, evaluation, and management: a scientific statement from the American Heart Association. Hypertension 72, e53–e90 (2018).
3. Freeman, M. W. et al. Phase 2 trial of baxdrostat for treatment-resistant hypertension. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2213169 (2022).
4. Schlaich, M. P. et al. Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial. Lancet 400, 1927–1937 (2022).
5. Acelajado, M. C., Hughes, Z. H., Oparil, S. & Calhoun, D. A. Treatment of resistant and refractory hypertension. Circ. Res. 124, 1061–1070 (2019).
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1. Progress towards improving blood pressure control;Nature Reviews Nephrology;2023-12-06
2. Taming resistant hypertension: The promise of novel pharmacologic approaches and renal denervation;British Journal of Pharmacology;2023-10-21
3. Silencing Angiotensinogen in Hypertension;New England Journal of Medicine;2023-07-20
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