Who’s afraid of replication-competent adenoviruses?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3300902.pdf
Reference14 articles.
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2. Lochmüller H . Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (ΔE1 + ΔE3) during multiple passages in 293 cells Hum Gene Ther 1994 5: 1485–1491
3. Hehir KM et al. Molecular characterization of replication-competent variants of adenovirus vectors and genome modifications to prevent their occurrence J Virol 1996 70: 8459–8467
4. Morgan D, Forgic I, Wisher MH . Safety considerations in the development of new retroviral and adenoviral vectors for gene therapy. In: Merten OW, Perrin P, Griffiths B (eds) . New Developments and New Applications in Animal Cell Technology Kluwer Academic Publishers: Dordrecht 1998 523–529
5. Imler JL et al. Novel complementation cell lines derived from human lung carcinoma A549 cells support the growth of E1-deleted adenovirus vectors Gene Therapy 1996 3: 75–84
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