Who’s afraid of replication-competent adenoviruses?

Author:

Fallaux F J,van der Eb A J,Hoeben R C

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference14 articles.

1. Louis N, Evelegh C, Graham FL . Cloning and sequencing of the cellular–viral junctions from the human adenovirus type 5 transformed 293 cell line Virology 1997 233: 423–429

2. Lochmüller H . Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (ΔE1 + ΔE3) during multiple passages in 293 cells Hum Gene Ther 1994 5: 1485–1491

3. Hehir KM et al. Molecular characterization of replication-competent variants of adenovirus vectors and genome modifications to prevent their occurrence J Virol 1996 70: 8459–8467

4. Morgan D, Forgic I, Wisher MH . Safety considerations in the development of new retroviral and adenoviral vectors for gene therapy. In: Merten OW, Perrin P, Griffiths B (eds) . New Developments and New Applications in Animal Cell Technology Kluwer Academic Publishers: Dordrecht 1998 523–529

5. Imler JL et al. Novel complementation cell lines derived from human lung carcinoma A549 cells support the growth of E1-deleted adenovirus vectors Gene Therapy 1996 3: 75–84

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