Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma

Author:

Barker S D,Dmitriev I P,Nettelbeck D M,Liu B,Rivera A A,Alvarez R D,Curiel D T,Hemminki A

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference18 articles.

1. Tomko RP, Xu R, Philipson L . The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsakieviruses. Proc Natl Acad Sci USA 1997; 94: 3352–3356.

2. Yang Y . Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004–2015.

3. Yang Y . Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. Gene Therapy 1996; 3: 137–144.

4. Bauerschmitz G, Barker S, Hemminki A . Adenoviral gene therapy for cancer – from vectors to targeted and replication competent agents. Int J Oncol 2002; 21(6): 1164–1174.

5. Curiel D . Strategies to adapt adenoviral vectors for targeted delivery. Ann NY Acad Sci 1999; 886: 158–171.

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