Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-β?-Reference-Cited by-同舟云学术

Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-β?

Published:2004-09-02 Issue:20 Volume:11 Page:1487-1496
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Song L,Wang J,Wang R,Yu M,Sun Y,Han G,Li Y,Qian J,Scott DW,Kang Y,Soukhareva N,Shen B

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/3302327.pdf

Reference25 articles.

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2. Schwartz RH . A cell culture model for T lymphocyte clonal anergy. Science 1992; 248: 1349–1356.

3. Zambidis ET, Scott DW . Epitope-specific tolerance induction with an engineered immunoglobulin. Proc Natl Acad Sci USA 1996; 93: 5019–5024.

4. Zambidis ET, Barth RK, Scott DW . Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients. J Immunol 1997; 158: 2174–2182.

5. Kang Y et al. Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: the IgG scaffold is important for induction and maintenance of immune hyporesponsiveness. Proc Natl Acad Sci USA 1999; 96: 8609–8614.

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