Nitroreductase-mediated cell ablation is very rapid and mediated by a p53-independent apoptotic pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3300873.pdf
Reference24 articles.
1. Moolten FL . Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy Cancer Res 1986 46: 5276–5281
2. Moolten FL, Wells JM, Heyman RA, Evans RM . Lymphoma regression induced by ganciclovir in mice being a herpes thymidine kinase transgene Hum Gene Ther 1990 1: 125–135
3. Chambers R et al. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma Proc Natl Acad Sci USA 1995 92: 1411–1415
4. Black ME, Newcomb TG, Wilson HMP, Loeb LA . Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy Proc Natl Acad Sci USA 1996 93: 3525–3529
5. Izquierdo M et al. Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy Gene Therapy 1996 3: 491–495
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