A newly modified SCG10 promoter and Cre/loxP-mediated gene amplification system achieve highly specific neuronal expression in animal brains
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3302779.pdf
Reference19 articles.
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2. Miyaguchi K, Maeda Y, Kojima T, Setoguchi Y, Mori N . Neuron-targeted gene transfer by adenovirus carrying neural-restrictive silencer element. Neuroreport 1999; 10: 2349–2353.
3. Navarro V, Millecamps S, Geoffroy MC, Robert JJ, Valin A, Mallet J et al. Efficient gene transfer and long-term expression in neurons using a recombinant adenovirus with a neuron-specific promoter. Gene Therapy 1999; 6: 1884–1892.
4. Millecamps S, Kiefer H, Navarro V, Geoffroy MC, Robert JJ, Finiels F et al. Neuron-restrictive silencer elements mediate neuron specificity of adenoviral gene expression. Nat Biotechnol 1999; 17: 865–869.
5. Schoenherr CJ, Anderson DJ . Silencing is golden: negative regulation in the control of neuronal gene transcription. Curr Opin Neurobiol 1995; 5: 566–571.
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