Immunization strategy against cervical cancer involving an alphavirus vector expressing high levels of a stable fusion protein of human papillomavirus 16 E6 and E7

Author:

Daemen T,Regts J,Holtrop M,Wilschut J

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference47 articles.

1. Münger K., Scheffner M., Huibregtse J.M., Howley P.M. . Interactions of HPV E6 and E7 with tumor suppressor gene products Cancer Surv 1992 12: 197 197

2. Porreco R. et al. Gynecological malignancies in immunosuppressed organ homograft recipients Obstet Gynecol 1975 45: 359 359

3. Johnson J.C. et al. High frequency of latent and clinical human papillomavirus cervical infections in immunocomprised human immunodeficiency virus-infected women Obstet Gynecol 1992 79: 321 321

4. De Bruijn M.L. et al. Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells Cancer Res 1988 58: 724 724

5. Daemen T. et al. Genetic immunization against cervical carcinoma: induction of cytotoxic T lymphocyte activity with a recombinant alphavirus vector expressing human papillomavirus type 16 E6 and E7 Gene Therapy 2000 7: 1859 1859

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