Bacterial DNA is implicated in the inflammatory response to delivery of DNA/DOTAP to mouse lungs
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3301097.pdf
Reference9 articles.
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2. Scheule RK et al. Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung Hum Gene Ther 1997 8: 689–707
3. Schwartz DA et al. CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract J Clin Invest 1997 100: 68–73
4. Krieg AM et al. CpG motifs in bacterial DNA trigger direct B-cell activation Nature 1995 374: 546–549
5. Freimark BD et al. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid:cationic lipid complexes J Immunol 1998 160: 4580–4586
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