Conditionally replicating viruses in cancer therapy

Author:

Connolly J B

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference24 articles.

1. Alemany R, Balague C, Curiel DT . Replicative adenoviruses in cancer therapy. Nat Biotech 2000; 18: 723–727.

2. Kirn D . Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer. Oncogene 2000; 19: 6660–6669.

3. Ganley I et al. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. Clin Cancer Res 2000; 6: 798–806.

4. Nemunaitis J et al. Selective replication an oncolysis in p53 mutant tumors with ONYX-015, and E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res 2000; 60: 6359–6366.

5. Papanastassoiu V et al. The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of priniciple study. Gene Ther 2002; 9: 398–406.

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