Function of a genetically modified human liver cell line that stores, processes and secretes insulin

Author:

Tuch B E,Szymanska B,Yao M,Tabiin M T,Gross D J,Holman S,Anne Swan M,Humphrey R K B,Marshall G M,Simpson A M

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference53 articles.

1. Bland BJ (ed). International Pancreas Transplant Registry Newsletter. 2001, p. 13.

2. Shapiro AMJ et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 343:230–238.

3. Brendel MD, Hering BJ, Schultz AO, Bretzel RG . International Islet Transplant Registry, Vol. 9, 2001.

4. Tuch BE et al. Recovery of human fetal pancreas after one year of implantation in the diabetic patient. Transplantation 1988; 46: 865–870.

5. Simpson AM et al. Functional expression of the human insulin gene in a human hepatoma cell line (HEP G2). Gene Ther 1995; 2: 223–231.

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