Long-term therapeutic levels of human alpha-1 antitrypsin in plasma after hydrodynamic injection of nonviral DNA
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3302065.pdf
Reference32 articles.
1. Crystal RG . The alpha 1-antitrypsin gene and its deficiency states. Trends Genet 1989; 5: 411–417.
2. Brantly ML et al. Use a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes. Chest 1991; 100: 703–708.
3. Garver Jr RI, Chytil A, Coutney M, Crystal R . Clonal gene therapy: transplanted mouse fibroblast clones express human alpha-1-antitrypsin gene in vivo. Science 1987; 237: 762–764.
4. Rosenfeld MA et al. Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo. Science 1991; 252: 431–432.
5. Kay MA et al. Expression of alpha 1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes. Proc Natl Acad Sci USA 1992; 89: 89–93.
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