Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3302021.pdf
Reference29 articles.
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2. Zabner J et al. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270: 18997–19007.
3. Dean DA, Dean BS, Muller S, Smith LC . Sequence requirements for plasmid nuclear entry. Exp Cell Res 1999; 253: 713–722.
4. Dean DA . Nucleocytoplasmic trafficking. In: Mahato RI (ed). Pharmaceutical Perspectives of Nucleic Acid-based Therapeutics. Harwood Academic Publishers: 2002, in press.
5. Fasbender A, Zabner J, Zeiher BG, Welsh MJ . A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia. Gene Therapy 1997; 4: 1173–1180.
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