Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

Author:

Mulvihill S,Warren R,Venook A,Adler A,Randlev B,Heise C,Kirn D

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference27 articles.

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2. Burris H et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial J Clin Oncol 1997 15: 2403–2413

3. Barton CM et al. Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer Br J Cancer 1991 64: 1076–1082

4. Pellegata N et al. K-ras and p53 mutations in pancreatic cancer: ductal and non-ductal tumors progress through different genetic lesions Cancer Res 1994 54: 1556–1562

5. Chang F, Syrjanen S, Syrjanen K . Implications of the p53 tumor-suppressor gene in clinical oncology J Clin Oncol 1995 13: 1009–1022

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