A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Δ24, for the treatment of advanced breast cancer

Author:

Ranki T,Kanerva A,Ristimäki A,Hakkarainen T,Särkioja M,Kangasniemi L,Raki M,Laakkonen P,Goodison S,Hemminki A

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference49 articles.

1. Bernard-Marty C, Cardoso F, Piccart MJ . Facts and controversies in systemic treatment of metastatic breast cancer. Oncologist 2004; 9: 617–632.

2. Hemminki A, Alvarez RD . Adenoviruses in oncology: a viable option? Biodrugs 2002; 16: 77–87.

3. Immonen A, Vapalahti M, Tyynela K, Hurskainen H, Sandmair A, Vanninen R et al. AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol Ther 2004; 10: 967–972.

4. Peng Z, Han D, Zhang S, Pan J, Tang P, Xiao S et al. Clinical evaluation of safety and efficacy of intratumoral administration of a recombinant adenoviral-p53 anticancer agent (Genkaxin®). Mol Ther 2003; 7 (Suppl. 2): 422 (Abstract 1096).

5. Xia ZJ, Chang JH, Zhang L, Jiang WQ, Quan ZZ, Liu JW et al. Phase III randomized clinical trial of intratumoral injection of E1B gene-deleted adenovirus (H101) combined with cisplatin-based chemotherapy in treating squamous cell cancer of head and neck or esophagus. Ai Zheng 2004; 23: 1666–1670.

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