Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis

Author:

Wildbaum G,Karin N

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference97 articles.

1. Alvord ECJ, Kies MW, Suckling AJ (eds) . Experimental Allergic Encephalomylitis: A Useful Model for Multiple Sclerosis, 1st edn Allen R Liss: New York 1984

2. MacFarlin D, MacFarland H . Multiple sclerosis New Engl J Med 1983 307: 1183–1188

3. Karin N et al. Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis J Immunol 1993 150: 4116–4124

4. Yednock TA et al. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin Nature 1992 356: 63–66

5. Karin N et al. Reversal of experimental autoimmune encephalomyelitis as soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of IFN-γ and TNF-α production J Exp Med 1994 180: 2227–2237

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