Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma

Author:

Becker K,Marchenko N D,Maurice M,Moll U M

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Reference40 articles.

1. Tweddle DA, Pinkerton CR, Lewis IJ, Ellershaw C, Cole M, Pearson AD . OPEC/OJEC for stage 4 neuroblastoma in children over 1 year of age. Med Pediatr Oncol 2001; 36: 239–242.

2. Vogelstein B, Lane D, Levine AJ . Surfing the p53 network. Nature 2000; 408: 307–310.

3. Keshelava N, Zuo JJ, Chen P, Waidyaratne SN, Luna MC, Gomer CJ et al. Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines. Cancer Res 2001; 61: 6185–6193.

4. Tweddle DA, Malcolm AJ, Bown N, Pearson AD, Lunec J . Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line. Cancer Res 2001; 61: 8–13.

5. Moll UM, LaQuaglia M, Benard J, Riou G . Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci USA 1995; 92: 4407–4411.

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