Radiation-induced apoptosis in the adult central nervous system is p53-dependent

Author:

Chow B M,Li Y-Q,Wong C S

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Reference37 articles.

1. Lowe SW, Schmitt EM, Smith SW, Osborne BA and Jacks T . (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847–849

2. Merritt AJ, Allen TD, Potten CS and Hickman JA . (1997) Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation. Oncogene 14: 2759–2766

3. Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, Lane DP and Hall PA . (1994) The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res. 54: 614–617

4. Enokido Y, Araki T, Tanaka K, Aizawa S and Hatanaka H . (1996) Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons. Eur. J. Neurosci. 8: 1812–1821

5. Kim SH, Chung CY and Son CH . (1998) Cell death by apoptosis in the neonatal mouse cerebellum following gamma-irradiation. Anticancer Res. 18: 1629–1632

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