Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism

Author:

Salvioli S,Storci G,Pinti M,Quaglino D,Moretti L,Merlo-Pich M,Lenaz G,Filosa S,Fico A,Bonafè M,Monti D,Troiano L,Nasi M,Cossarizza A,Franceschi C

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Reference53 articles.

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2. Brink AA, Oudejans JJ, van den Brule AJ, Kluin PM, Horstman A, Ossenkoppele GJ, van Heerde P, Jiwa M and Meijer CJ . (1998) Low p53 and high bcl-2 expression in Reed-Sternberg cells predicts poor clinical outcome for Hodgkin's disease: involvement of apoptosis resistance? Modern Pathol. 11: 376–383

3. Pepper C, Hoy T and Bentley P (1998) Elevated Bcl-2/Bax are a consistent feature of apoptosis resistance in B-cell chronic lymphocytic leukemia and are correlated with in vivo chemoresistance. Leuk. Lymphoma. 28: 355–361

4. McConkey DJ, Chandra J, Wright S, Plunkett W, McDonnell TJ, Reed JC and Keating M (1996) Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX. J. Immunol. 156: 2624–2630

5. Igney FH and Krammer PH . (2002) Immune escape of tumors: apoptosis resistance and tumor counterattack. J. Leukoc. Biol. 71: 907–920

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