Reconstitution of telomerase activity combined with HPV-E7 expression allow human preadipocytes to preserve their differentiation capacity after immortalization

Author:

Darimont C,Zbinden I,Avanti O,Leone-Vautravers P,Giusti V,Burckhardt P,Pfeifer A M A,Macé K

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Reference26 articles.

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2. Shay JW, Wright WE and Werbin H (1991) Defining the molecular mechanisms of human cell immortalization. Biochim. Biophys. Acta. 1072: 1–7

3. Huschtscha LI and Holliday R (1983) Limited and unlimited growth of SV40-transformed cells from human diploid MRC-5 fibroblasts. J. Cell Sci. 63: 77–99

4. Halvorsen TL, Leibowitz G and Levine F (1999) Telomerase activity is sufficient to allow transformed cells to escape from crisis. Mol. Cell Biol. 19: 1864–1870

5. Darimont C, Avanti O, Tromvoukis Y, Vautravers-Leone P, Kurihara N, Roodman GD, Colgin LM, Tullberg-Reinert H, Pfeifer AM, Offord EA and Mace K (2002) SV40 T antigen and telomerase are required to obtain immortalized human adult bone cells without loss of the differentiated phenotype. Cell Growth Differ. 13: 59–67

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