Functional significance of the perforin/granzyme cell death pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri911.pdf
Reference126 articles.
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3. Sarin, A. et al. Target-cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases. Immunity 6, 209–215 (1997).References 2 and 3 were the first to show that granzyme B (reference 2 ) and CTLs (reference 3 ) can kill target cells independently of caspase activation.
4. Nagata, S. & Golstein, P. The Fas death factor. Science 267, 1449–1456 (1995).
5. Van Parijs, L. & Abbas, A. K. Role of Fas-mediated cell death in the regulation of immune responses. Curr. Opin. Immunol. 8, 355–361 (1996).
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