Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice
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Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-26599-8.pdf
Reference47 articles.
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3. Tester, D. J., Will, M. L., Haglund, C. M. & Ackerman, M. J. Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing. Heart rhythm: the official journal of the Heart Rhythm Society 2, 507–517, https://doi.org/10.1016/j.hrthm.2005.01.020 (2005).
4. Abbott, G. W. KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing? Expert review of clinical pharmacology 6, 49–60, https://doi.org/10.1586/ecp.12.76 (2013).
5. Abbott, G. W. The KCNE2 K(+) channel regulatory subunit: Ubiquitous influence, complex pathobiology. Gene 569, 162–172, https://doi.org/10.1016/j.gene.2015.06.061 (2015).
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