UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication-Reference-Cited by-同舟云学术

UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication

Published:2021-03-18 Issue:1 Volume:11 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Biasin Mara,Bianco Andrea,Pareschi Giovanni,Cavalleri Adalberto,Cavatorta Claudia,Fenizia Claudio,Galli Paola,Lessio Luigi,Lualdi Manuela,Tombetti Enrico,Ambrosi Alessandro,Redaelli Edoardo Maria Alberto,Saulle Irma,Trabattoni Daria,Zanutta Alessio,Clerici Mario

Abstract

AbstractThe potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-021-85425-w.pdf

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