Author:
Sharma Mridula,Barai Ram Shankar,Kundu Indra,Bhaye Sameeksha,Pokar Khushal,Idicula-Thomas Susan
Abstract
AbstractPolyCystic Ovary Syndrome KnowledgeBase (PCOSKBR2) is a manually curated database with information on 533 genes, 145 SNPs, 29 miRNAs, 1,150 pathways, and 1,237 diseases associated with PCOS. This data has been retrieved based on evidence gleaned by critically reviewing literature and related records available for PCOS in databases such as KEGG, DisGeNET, OMIM, GO, Reactome, STRING, and dbSNP. Since PCOS is associated with multiple genes and comorbidities, data mining algorithms for comorbidity prediction and identification of enriched pathways and hub genes are integrated in PCOSKBR2, making it an ideal research platform for PCOS. PCOSKBR2 is freely accessible at http://www.pcoskb.bicnirrh.res.in/.
Funder
Department of Biotechnology, Ministry of Science and Technology, India
Department of Health Research, India
Publisher
Springer Science and Business Media LLC
Cited by
12 articles.
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